Welcome to the Spatial Omics and Bioinformatics (SOMa)Lab
The SOMa Lab develops and applies next-generation single-cell and spatial multi-omic technologies, alongside advanced computational methods, to decode how cells organize and interact to sustain healthy tissues, and how these interactions collapse in disease.
Our Approach
We connect clinical samples and patient-derived models with our developed spatial technologies, and biology‑ and measurement‑aware computational approaches to push the boundaries of what can be measured and understood in tissues, generating unprecedented insight into the cellular basis of health and disease.
Our Mission & Philosophy
We are a group of curiosity‑driven scientists motivated by problems that matter to researchers today. To identify and tackle the right questions, we rely on multi-disciplinary collaborations spanning academia, hospitals, and industry partners. Our long-term goal is to translate our findings into actionable outcomes, enabling biomarker discovery, patient stratification, and therapeutic development.
Explore SOMa Lab
Our Research
We are developing novel single-cell and spatial multi-omic technologies, together with advanced computaional methods to push the boundary of what can be measured and understood in tissues. We are using these methods to focus on diverse areas of biology such as obesity, diabetes, and oncology.
Our Publications
Our publications span technology development, computational methods, and disease-focused studies. Read more about our recent work on a new spatial transcriptomics platform, adipose tissue dysfunction in obesity, and integrative analysis of scRNA-seq and snRNA-seq datasets.
Our Team
Prof. Anushka Gupta is the Principal Investigator of the SOMa Lab. As a new lab, we are actively looking for highly motivated and curious undergraduate, graduate (Masters/PhD), post-doctoral, and project associate candidates to join our team! To apply, please contact Prof. Gupta and include a CV with your research interests.
Collaborators and Partnerships
We are always looking to collaborate with researchers, biologists, and clinicians to identify biological questions where spatial context, multimodal measurements, and integrative analysis are essential for new insights. To explore potential collaborations, reach out at agupta@iitm.ac.in.